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Parasitology Department

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About
...

The Department is responsible for teaching Medical Parasitology to the 2nd year pre-clinical MBBS students.

With the rapid development in infrastructure and the introduction of new courses, the Department of Parasitology also contributes in teaching other courses at Diploma, Bachelor of Science and Master levels. Among the courses taught at the Diploma level are Nursing and Medical Laboratory Technologist. At the first degree level are the MBBS Phase II, Pharmacy and Biomedical Science courses. Courses at the postgraduate level include the Master in Pathology (MPath) and Master in Public Health (MPH). The Department has postgraduate students pursuing their Master by research and PhD courses.

Since this Department was established, it has produced many Master and PhD holders through research both locally and internationally. This Department has also been involved in offering consultation and teaching to Royal College of Medicine Perak (RCMP), Kolej Universiti Islam Malaysia (KUIM), UiTM and Institute of Medical Research, Malaysia.

This Department is also a reference centre for parasitic diseases for government and private hospitals from around the country. We hope, one day this Department will be recognized as aNational Diagnostic Centre for Parasitic Infections.

The Department also provides services in detection of Cryptosporidium spp. oocysts andGiardia spp. cysts in recreational and sewage treatment plants.

Changing and upgrading teaching and research methodologies have to be continuously implemented in the department in order to meet the various demands. In this context, the product and diagnostic analysis achieved would be the bench mark (gold standard) that is acceptable by the clients.

 
History
...

Past and Present Head of Department

 

 

 

Prof. Dr. R. Bisseru
1967 – 1972

Prof. Dr. A.S. Dissanaike
1972 – 1979

Assoc. Prof. Dr. S. Ramalingam
1979

     

 

Assoc. Prof. Dr. V. Thomas
1984

Prof. Dr. S.P. Chua
1986 – 1989

Assoc. Prof. Dr. K. Chandra Shekhar
1990

     

 

 

 

Dr. Nik Najib Nik Abdul Rahman
1990

Prof. Dr. B. Sinniah
1992

Assoc. Prof. Dr. Johari Surin
1994;
2005 – August 2006

     

 

 

 

Prof. Dr. Khairul Anuar Abdullah
1995 – 2004

Assoc. Prof. Dr. Rohela Mahmud
2000;
September 2006 – current

 
 
 
Staff
...
 
Academic Programme
...
 
Research
...

Research Interest

The Department of Parasitology, places utmost importance in research on parasitic diseases and emerging parasites. The department has acquired many grants and translated its activities in the form of publications and presentations at national and international conferences.

Studies on pathogenicity and immunological characterization of Acanthamoeba species isolated from clinical and environtmental samples are currently being carried out. Development of recombinant antigens for the diagnosis of toxoplasmosis continues to be a major focus. Many molecular markers have been successfully identified and the search for a better diagnostic method is being developed. The department continues to perform sero-prevalence studies of Toxoplasmosis in both immunocompetent and immunocompromised patients to determine base-line data and infection rates. Emerging parasitic infections have prompted the Department to develop molecular technology for Cryptosporidiosis.

The department also gives emphasis on studies concerning detection of Cryptosporidium andGiardia in recreational and sewage water. Studies on Cryptosporidium and Giardia in HIV patients are also being carried out. The department is also looking into the viability and genotyping of Cryptosporidium. Studies on the biology, immunology and pathology ofBlastocystis hominis continues to be one of the core research activities. The reactivity ofBlastocystis isolates with monoclonals using immunoperoxidase technique is currently being evaluated. We are also trying to establish the detection protocol for Blastocystis cysts from water samples. The emphasis has also been in comprehending the biology and pathogenicity of Trichomonas vaginalis and microsporidium. The search for newer drugs against parasitic infections continues with emphasis on screening for herbal extracts from Malaysian traditional medicinal plants against malaria. The understanding of the mechanism and mode of action at molecular levels of these drugs against the target organisms provide the basis for the search of newer allopathic and herbal extracts against these organisms. Work is also being carried out on gene expression analysis of erythrocyte infected withPlasmodium sp. Work on molecular genetics and detection of Brugia pahangi andPlasmodium knowlesi (zoonotic simian malaria parasite) are currently being carried out. There are also efforts to look into the In vitro and in vivo studies of Plasmodium knowlesi. On the frontiers of entomological research, study on Aedes mosquitoes has become the thrust activity in the department. Research in entomotoxicology of forensically important insects and study on diversity of forensically important fly species are being carried out. These activities and available expertise have established the Department to be a national referral center for emerging and remerging parasitic infections.

On Going Research

  1. Prof. Dr. Johari Surin. Application of Mitochondrial DNA Analysis in the Identification of Cadaveric Dipteran Larvae for Postmortem Interval Estimation (PMI).
  2. Prof. Dr. Johari Surin. Dynamic Trends of the Phylogenetic Taxonomy of water borne protozoan parasites of man, animal agents and the environment in Malaysia based on Ssu Rrna and Gp60 Gene.
  3. Prof. Dr. Johari Surin. Phylogenetic Study of Cryptosporidium Isolated from Human, Animal and Aquatic Environment in Malaysia based on SSU rRNA and GP60 Genes.
  4. Prof. Dr. Johari Surin and Assoc. Prof. Dr Yvonne Lim Ai Lian. Genotyping ofCryptosporidium in Immunocompromised Patients.
  5. Prof. Dr. Johari Surin and Nor Adzliyana Binti Yaacob. Entomotoxicology of Forensically Important Insects and Its Effects on Larval Growth, Rate of Development and the Post Mortem Interval Estimation.
  6. Prof. Dr. Johari Surin and Asma Iqbal. Detection and Molecular Characterization of Cryptosporidium in HIV patients.
  7. Prof. Dr. Rohela Mahmud. Molecular Epidemiology of Microsporidia Isolated from Immunocompromised Patients.
  8. Prof. Dr. Rohela Mahmud and Azdayanti binti Muslim. Filariasis in Sub-Urban Areas of Klang Valley : Parasitological, Entomological and Molecular Studies.
  9. Prof. Dr. Jamaiah Ibrahim. Morphological Characterization oh Human Parasites Using Electron Microscopy.
  10. Prof. Dr. Suresh Kumar. Studies of the Correlation Between Biochemical and Molecular Aspects of Blastocystis with Fundamental Immunopathological Mechanisms During In vitro and In vivo.
  11. Prof. Dr. Suresh Kumar. Molecular and Biochemical Characterization of Isolates and Life Cycle Stages of Blastocystis hominis Isolated from Patients Suffering from Irritable Bowel Syndrome.
  12. Prof. Dr. Suresh Kumar and Lee II Li. Establishing the Detection Protocol forBlastocystis Cysts from Water Samples.
  13. Assoc. Prof. Dr. Zurainee Mohamed Nor. Study on the Anti-Malarial Activities of Malaysian Traditional Medicinal Plants.
  14. Assoc. Prof. Dr. Zurainee Mohamed Nor and Abdulelah Hussein Ahmad Aladhroey. In vivo Anti-Malarial Study on Malaysian Medicinal Plants. PS
  15. Assoc. Prof. Dr. Fong Mun Yik. Molecular Studies of Zoonotic Simian Malaria Parasite Plasmodium knowlesi.
  16. Assoc. Prof. Dr. Fong Mun Yik. Determination of Factors that Contribute to Protection Relationship of Pre-Existing Neutralizing Antibody Level.
  17. Assoc. Prof. Dr. Fong Mun Yik and Asha a/p Thanabalan. Molecular Genetic of the Filarial Worm Brugia pahangi.
  18. Assoc. Prof. Dr. Fong Mun Yik and Marshita binti Mohd Idris. Expression ofToxoplasma gondii Dense Granule Antigen (GRA2) in the Yeast Pichia pastoris for use in serodiagnosis of Toxoplasmosis.
  19. Assoc. Prof. Dr. Fong Mun Yik and AbdulSalam Mohammed Al-Mekhlafi. Molecular Epidemiology of Malaria Parasite in Yemen. PS175/2008C (RM28,500.00).
  20. Assoc. Prof. Dr Veeranoot Nissapatorn. Detection of Toxoplasma Responses in Saliva and Urine Samples of Patients with Psychological Disorders.
  21. Assoc. Prof. Dr Yvonne Lim Ai Lian. Helminth Infection and Asthma in the Orang Asli Communities.
  22. Assoc. Prof. Dr Yvonne Lim Ai Lian and Romano Ngui. Epidemiological Distribution of Soil-Transmitted Helminthes Infection and Its Association with Asthma among the Orang Asli Communities in Malaysia.
  23. Dr. Tan Tian Chye. Establishment of Continuous In vitro Culture of the Malaria Parasite Plasmodium knowlesi Obtained from Human.
  24. Dr. Noraishah Mydin Hj. Abdul Aziz. Does Closure of the Spinal Neural Tube Occur Asymmetrically?
  25. Dr. Noraishah Mydin Hj. Abdul Aziz. The Role of T-Cadherin During Adhesion and Fusion of the Spinal Neural Tube.
  26. Dr. Lau Yee Ling. Recombinant expression of Toxoplasma gondii Surface Antigens SAG1-SAG2.
  27. Dr. Lau Yee Ling. Development of DNA and Recombinant Vaccines againstToxoplasma gondii infection.
 
Services
...

WHAT ?

Para :SEAD is the diagnostic division of the Department of Parasitology, a component part of the “Unit Pengurusan Makmal”, University Malaya Medical Centre.  It offers the following services:

 

 KATEGORI

ITEM

UJIAN YANG DIJALANKAN

Caj
(RM)

PAR

BLOOD

BLOD 0001

Malaria – direct smear

16.00

   

BLOD 0002

Filaria – direct smear /  concentration technique

16.00

 

SERO

SERO 0001

Malaria – ELISA

50.00

   

SERO 0002

Filariasis – ELISA subclassing

120.00

     

Filariasis – Brugia Rapid

30.00

     

Filariasis – Wuchereria bancrofti Rapid

30.00

   

SERO 0003

Schistosomiasis – IHA

60.00

   

SERO 0004

Amoebiasis – IHA

50.00

   

SERO 0005

Toxoplasmosis – ELISA (IgG & IgM)

50.00

   

SERO 0006

Toxoplasmosis – ISAGA

120.00

   

SERO 0007

Echinococcosis – IHA

50.00

   

SERO 0008

Leishmaniasis – IHA

50.00

   

SERO 0009

Toxocariasis

50.00

   

SERO 0010

Cysticercosis

50.00

   

SERO 0011

Trypanosomiasis

50.00

 

PCR

 

Malaria

70.00

     

Toxoplasmosis

70.00

 

FAECES

FAES 0001

Faecal specimen : direct examination, concentration technique

16.00

   

FAES 0002

Faecal specimen : staining

16.00

 

URINE

0001

Schistosoma haematobium

16.00

 

VAGINAL
DISCHARGE

0001

Trichomonas vaginalis

16.00

 

BONE
MARROW

0001

Leishmania donovani – direct microscopy + staining

16.00

 

CULTURE

CULT 0001

Acanthamoeba (Corneal scrapping)

30.00

   

CULT 0002

Blastocystis

30.00

   

CULT 0003

Trichomonas vaginalis

30.00

 

FORENSIC

FORE 0001

Identification of maggots

30.00

WHERE ?

servicepic1_para

Blocks N & O, Level 5,
Faculty of Medicine
University of Malaya

 

WHEN ?

8.00 AM – 5.00 PM
MONDAY – FRIDAY

WHOM ?

For any inquiries regarding diagnosis and results,
Please call this number :

  • Tel: 03-79674744 (Scientific Officer)
  • Tel: 03-79675735 (Para:SEAD Lab)
  • Tel: 03-79674963 (General Office)
  • Fax. No: 03-79674754
 
Future Plan
...

1 year

  • Accreditation of diagnostic laboratory by Standards Malaysia.
  • Organise a Workshop on Mosquitoes of Medical Importance.
  • Organise a National Workshop on Free Living Amoebas.
5 year

 

  • Each academic staff is to supervise students for Master in Medical Science or PhD
  • Each academic staff is to obtain an IRPA grant or other fundings for research purposes
  • Collaboration in the field of research with institute within and outside the country:
    • Parasitic Diseases Unit, World Health Geneva
    • Parasitic Diseases Unit, Hanoi, WHO
    • Department of Parasitology, Mahidol University, Bangkok
    • Bio-Medical Centre, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
    • Department of Parasitology, University of Indonesia.
  • To set up a Centre for Neglected Parasitic Diseases.
  • To renovate postgraduate student room
  • To renovote satellite animal room.
Last Updated: 30/10/2018