Pharmacogenomics Laboratory - Director

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PHARMACOGENOMICS LABORATORY - Director

                            | Director | Academic and Support Staff | Postgraduate Students |


 

Prof. Dr. Zahurin Binti Mohamed
(Director, Pharmacogenomics Laboratory)

Head of Department,
Department of Pharmacology,
Faculty Of Medicine, University of Malaya,
50603 Kuala Lumpur, Malaysia

ACADEMIC QUALIFICATION
PHD, DUNDEE UNIVERSITY, ABERDEEN, SCOTLAND
BSC, DUNDEE UNIVERSITY, ABERDEEN, SCOTLAND
SPM, Hastings College of Further Education, Hastings, Sussex
Tel. No. (Office) : +603-7967 5725
Fax No. : +603-7967 4791
E-Mail Address : zahurin@um.edu.my


Publications (2009):

  1. Comparative bioavailability study of two salbutamol tablets in healthy adult volunteers. Z. Chik1, R.C. Basu, R. Pendek, T.C. Lee and Z. Mohamed. International Journal of Clinical Pharmacology and Therapeutics, Vol. 47- No 6/2009 (413-418). 

  2. Role of ABCB1 C3435T variant in response to antiepileptic drugs in epilepsy: A review. Haerian, BS, Mohamed Z, Mohamed EHM, Lim KS, Tan HJ, Tan CT, Raymond AA. Med & Health 2009; 4(2): 64-74

Presentations at Conferences:

  1. ABCB1/MDR1 C3435T polymorphism in epilepsy patients receiving carbamazepine. BS Haerian, Z Mohamed, CT Tan, AA Raymond, KS Lim, HJ Tan, EHM Mohamed and VL Raj. 8th Biennial Convention of the ASEAN Neurological Association (ASNA) & Neurosciences 2009, 20th Annual Scientific Meeting of the Malaysian Society of Neurosciences 2009. 1st – 4th April 2009. Berjaya Times Square Hotel & Convention Centre, Kuala Lumpur (oral)

  2. Association of G-1438A Polymorphism of 5HT2A Receptor with Schizophrenia in Three Ethnic Groups in Malaysia. Zahurin Mohamed. American Psychiatric Association Annual Meeting. May 16-21, 2009. San Francisco, USA (oral). Accepted but was not able to present.
  3. Association between the serotonin transporter gene and major depressive disorder in three major ethnic groups in Malaysia. Nor Zainal, Zahurin M, Lian L Hoong, Vijaya L Raj, Elsa M Mohamed, Loke Ai Chin. American Psychiatric Association Annual Meeting. May 16-21, 2009. San Francisco, USA (Poster)
  4. SCN1A polymorphism in epilepsy patients receiving carbamazepine. BS Haerian1, EHM Mohamed1, KS Lim2, HJ Tan3, VL Raj1, CT Tan2, AA Raymond3, Z Mohamed1 . 16th International Congress of Neurology & Clinical Electrophysiology of Iran. 19-22 May 2009. Iranian Journal of Neurology. Vol 8 Supplement 1, Spring 2009
  5. Association of ABCB1 (MDR1) and SCN1A polymorphism with resistance to carbamazepine in Malaysian epileptic patients. Batoul Sadat Haerian, EHM Mohamed, Z.Mohamed, VL Raj, KS Lim and CT Tan. Fifth Epilepsy Congress, Tehran 4-6 Nov 2008
  6. G-2458A Lep gene polymorphism is associated with body mass index (BMI) in the Malaysian Population. YD Apalasamy, FM Moy, S Rampal, AM Bulgiba and Z Mohamed. International Conference on Personalised Medicine and 5th Joint Conference on Pharmacogenetics. 19-20 September 2009. Hong Kong.
  7. Association between single nucleotide polymorphisms of FAAH gene and GSTP1 gene with addiction to stimulants in the Malaysian population. MS Sim, VL Raj, A Hatim and Z Mohamed. International Conference on Personalised Medicine and 5th Joint Conference on Pharmacogenetics. 19-20 September 2009. Hong Kong.
  8. Association of genetic polymorphism in the human pregnane X receptor/NR112 with response to carbamazepine in epilepsy. BS Haerian, EHM Mohamed, KS Lim, HJ Tan, CT Tan, AA Raymond, SM Zain and Z Mohamed. International Conference on Personalised Medicine and 5th Joint Conference on Pharmacogenetics. 19-20 September 2009. Hong Kong.
  9. Association Of TCF7l2 Gene Polymorphisms With Type 2 Diabetes Mellitus In Malaysia: A Preliminary Report. Muhammad Huzaimi bin Haron , Z Mohamed, R Pendek and NA Abdullah.. The 15th th Congress of the ASEAN Federation of Endocrine Societies (AFES2009). Oral. Thailand.

Research Funds:

  1. UMRG Grant. Association of Selected Candidate Genes With Response to Antiepileptic Drugs. Zahurin Mohamed. RG099/09HTM. RM85,000. April 2009

  2. UMRG Grant. Variation across candidate genes and its role in the development of non-alcoholic fatty liver disease, and its complications in patients with metabolic syndrome. Rosmawati Mohamed. RG069/09HTM. RM91,000. April 2009
  3. UMRG Grant. Case-Control Study in determining the risk factors for the occurrence of pre-term birth in Malaysian Population. Asmah Mastor. RG005/09HTM. RM95,000. April 2009.
  4. UMRG Grant. Association of candidate genes predisposing to obesity in Malaysian Subjects. Sanjay Rampal. RG075/09HTM. RM98,000. April 2009 . PS383/200 Allocation: RM 26,000.00
  5. UMRG Grant . Pharmacogenomic Study on Bipolar Disorders: A Case-Control Study. Gene Analysis Study of Selected Candidate Genes and Regulation of Gene Expression in Bipolar Disorder Patient on Response to Quetiapine Medication. Sharmilla A/P Kanagasundram. RM 50,200.00.
Postgraduate Students Supervision:

2007/2008  Wan Ching Lee  Pharmacogenetics of schizophrenia  Masters of Med. Science
2007/2008  Sim Maw Shin  Pharmacogenomics of Drug Abuse  Masters of Med. Science
2007/2008  Loke Ai Chin  Pharmacogenomics of Major Depression  Masters of Med. Science
2007/2008  Didi Erwandi Bin Mohamad Haron  Pharmacokinetics and Drug Analysis  Masters of Med. Science
2008/09  Shamsul Mohd Zain  Pharmacogenomics of Schizophrenia  Bachelor of Biomedical Sc.
2008/2009  Mohd Izwan Zainol  Polymorphism of the T102C Serotonin 2A Receptor Gene in multiethnic patients with major depressive disorder and its association with suiocidal behaviour  Bachelor of Biomedical Sc. 
2008/2009  Mohd Aizat Mohd Zain  Relationship between T102C polymorphism of the 5HT 2A receptor gene and occurrence of psychosis in patients with schizophrenia  Bachelor of Biomedical Sc.
2007/2008  Dr Muhammad Huzaimi Haron  Pharmacogenomics  Masters of Med. Science
2008/09  Batoul Sadat Haerian  Pharmacogenomics of Epilepsy  PhD 
2009/2010  Yamuna Devi Apalasamy  Pharmacogenomics  Masters of Med. Science
2009/2010  Soobitha Subenthiran  Population Pharmacokinetics and Pharmacogenomics  Masters of Med. Science
2009/10  Siti Zaleha Suki  Pharmacogenomics of Pre-Term Birth  Masters of Med. Science
2009/2010  Mohd Aizat Mohd Zain  Gene Analysis Study of selected candidate genes in Bipolar Disorder  Masters of Med. Science
2009/2010  Shamsul Bin Mohd Zain  Variation across candidate genes and its role in the development of non-alcoholic fatty liver disease  Masters of Med. Science
2009/2010  Siti Norsyuhada Mohd Roffeei  Pharmacogenomics of Schizophrenia  Masters of Med. Science
2009/2010  Afiqah Alyaa Binti Md Fuzi  Pharmacogenomics of Endometrial Cancer  Masters of Med. Science
2009/2010  Lee Ern Chi  The role of CYP2D6 in Malaysian Breast Cancer patients treated with tamoxifen  Masters of Med. Science


Workshops Attended:

  1. Workshop on INTERNAL QUALITY AUDITING OF MS ISO/IEC 17025:2005. 23-24 December 2009. Training by Infokinetics Sdn Bhd

  2. Workshop on MS ISO/IEC 17025:2005 INTRODUCTION AND UNDERSTANDING. 14TH April 2009. Training by Infokinetics Sdn Bhd.
  3. 2009 Intensive Bioethics Course. 27 November – 3 December 2009. Alexandra, Victoria, Australia. Organised by Monash University.
  4. Workshop on the Establishment of a National Bioethics Committee. 19 June 2009. Kuala Lumpur. Organised by MOSTI and Ministry of Women, Family and Community Development.
  5. Workshop on Whole genome-based association studies for SNP and CNV-based approaches. 12 October 2009. Institute of Medical Molecular Biotechnology, UiTM.
  6. Workshop on Organisation for Economic cooperation and development (OECD) Good Laboratory Practice (GLP) Documents to test facilities. 3-5 Aug 2009
  7. Bengkel Pemantapan Kurikulum Kursus Penilaian Tahap Kecekapan (PTK) Bagi Skim Perkhidmatan Pensyarah Gred DS/DU/DUG 45-54. Anjuran Bahagian Sumber Manusia, UM. 28-29 Januari 2009
  8. Bengkel Panel temuduga Program Ijazah Luar Negara 2009. Melaka. 4-6 March 2009. Anjuran Jabatan Perkhidmatan Awam.
  9. A Creativity Workshop on Foresight – Creating scenarios for the future. 23 June 2009. Organised by Faculty of Education UM
  10. Bengkel Pusat Pembangunan Pelajar Universiti Malaya (UMSDC). 18 Julai 2009. Kuala Lumpur. Organised by Pejabat Naib Canselor, UM.
  11. Bengkel Pemantapan Nilai-nila Teras UM bagi Jabatan Farmakologi. Julai 2009.
  12. Sijil Penyertaan bagi Kursus Pengajian Bahasa Arab Untuk Orang Awam. 24 Januari 2009
  13. ESQ Basic Training. 9-11th Jan 2009
  14. ESQ Mission and Character Building. 31st Jan – 1st Feb 2009.

External Examiners:

  1. 2nd Part of the Second Professional Examination, Pharmacology Subject, Kulliyah of Dentistry, International Islamic University Malaysia. June 2009

  2. Multiresidue determination of quinolone and chloramphenicol in poultry muscles from Malaysian processing plants by high performance liquid chromatography tandem mass spectrometry. Marni Sapar. Master in Medical Science. July 2009. To be conferred by University of Malaya.
  3. Effects of the Extracts and Active Constituents of Hempedu Bumi, Pegaga, and Misai Kucing on Cytochrome P450 Enzymes in Human Liver. External Examiner. Thesis by Pan Yan for the Degree of Philosophy to be conferred by the International Medical University. July 2009.
  4. The Predictive Value of Single Nucleotide Polymorphism of the Human Tumour Necrosis Factor-Alpha and Interleukin 10 in Human Gestational Diabetes Mellitus. External Examiner. Thesis by Shabnam Montazeri for Doctor of Philosophy (Community Health) to be conferred by the International Medical University. July 2009.
  5. Teratogenicity Study of Hempedu Bumi (Angrographis Paniculata) in Rats. External Examiner. Thesis by Noordalilati Binti Muhd Noor. PhD. July 2009.

Administration and Other Activities:

  1. National Level:
    1. Ahli Jawatankuasa Kebangsaan Penyelidikan Klinikal (National Clinical Research Committee), chaired by the Director General of Health, Tan Sri Ismail Merican
    2. Ahli Jawatankuasa Equivalence Kebangsaan (National Bioequivalence Committee)
    3. Ahli Jawatankuasa Protem bagi National Bioethics Committee
    4. Pengerusi Jawatankuasa Penghakiman dan Penilaian bagi PECIPTA 2009. (Ekspo Antarabangsa Penyelidikan dan Ciptaan). Peringkat Kebangsaan. Anjuran Kementerian Pengajian Tinggi dan Universiti Malaya
    5. Panel Temuduga Program Ijazah Luar Negara (PILN) 2009

  2. University and Faculty Level:
    1. Panel Tattertib Pelajar. Perlantikan Naib Canselor Julai 2009
    2. Jawatankuasa Penilaian Skim Geran Penyelidikan Fundamental (FRGS) Kementerian Pengajian Tinggi bagi UM (mulai December 2008 hingga December 2010
    3. Ahli Panel Penilaian Tahap Kecekapan (PTK) Bagi Skim Perkhidmatan Pensyarah Gred 45/51 Tahap Kecekapan (TK) 3 & 4 Tahun 2009 hingga 2010.
    4. Ahli Think-Tank bagi University of Malaya Student Development Centre di bawah naungan Timbalan Naib Canselor (Akademik & Antarabangsaan).
    5. Panel Penilai Pusat Penyelidikan. Perlantikan oleh Timbalan Naib Canselor (Penyelidikan dan Innovasi). April 2009
    6. Ketua Makmal Farmakogenomiks, Fakulti Perubatan, UM (mulai 10 Julai 2008 – Julai 2010)
    7. Koordinator Kursus MBBS bagi Farmakologi (15 Jun Julai 2009)
    8. Ahli Jawatankuasa Ijazah Tinggi Fakulti Perubatan, Wakil Jabatan Pra-Klinikal (mulai 6 Jun 2008 – Jun 2010)

  3. Non-Government Oraganisations (NGO)
    1. Ahli Jawatankuasa Coalition of NGOs against the persecution of Palestinians (COMPLETE). Deputy Awareness Subcommittee. Jan 2009-Jan 2010
    2. Ahli Jawatankuasa Viva Palestina Malaysia. Chairman Awareness Subcommittee. Jan 2010 till now
    3. Ahli Jawatankuasa Kanwork (Cancer Network)
    4. Ahli Jawatankuasa Badan Kebajikan Taman Tun Dr Ismail (BAKTI)
    5. Penasihat Persatuan Siswa-Siswi Perubatan Universiti Malaya (PSIPUM) semenjak 1994
    6. Ahli Jawatankuasa bagi Bengkel UPSR bagi Science. Organised by Taman Tun Dr Ismail Residents’ Association

  4. Invited Talks(NGO)
    1. Good Clinical Practice (GCP) Workshop. Informed Consent. July 2009. Organised by Pusat Perubatan Hospital Universiti Kebangsaan.
    2. Good Clinical Practice (GCP) Workshop. Informed Consent. Ethics Committee. June 2009. Organised by University of Malaya Medical Centre.
    3. Workshop on Research in Orthopaedic Surgery. Research Funding. Organised by Department of Orthopaedic Surgery, UM. June 2
    4. Penasihat Persatuan Siswa-Siswi Perubatan
 
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Department
of Pharmacology,

Faculty of Medicine,
University of Malaya,
50603 Kuala Lumpur,
MALAYSIA

Tel : +603-7967 4702/4703
Fax : +603-7967  4791

Email: zahurin@um.edu.my

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