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Pharmacy Department

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About
...

A four year Bachelor of Pharmacy [B. Pharm. (Hons)] course under semester system is offered to Malaysian undergraduates. The undergraduate programme consists of 44 core pharmacy modules under five disciplines, Pharmaceutical Chemistry, Scientific Basis of Therapeutics, Pharmaceutical Technology, Clinical Pharmacy and Pharmacy Practice.

Postgraduate programmes by research leading to MSc and PhD degrees are offered to both qualified Malaysian and overseas students. The research programmes encompass various areas of pharmaceutical sciences, including medicinal chemistry, natural products chemistry, drug action, drug delivery, pharmacoenconomics, pharmacoepidemiology and evidence based pharmacotherapy related to clinical and pharmacy practice.

To support these activities, the department is equipped with state-of-the-art research tools for biological chemistry, analytical chemistry and formulation research such as a pharmaceutical pilot plant facility for scale up experimental production of tablets and capsules, and microplate scintillation and luminescence counter, cell harvester and robotic liquid handling system for medium and high throughput biomolecular assays. These facilities are supplemented through collaborative work with researchers in other departments and faculties at the University of Malaya (UM), the Forest Research Institute Malaysia (FRIM), the Forest Research Center (FRC), Universiti Kebangsaan Malaysia (UKM), Universiti Putra Malaysia (UPM), and the pharmaceutical industry.

The research projects conducted at the Department are largely funded by grants from University of Malaya, the Intensification of Research in Priority Areas (IRPA) and pharmaceutical companies. To date the Department has successfully secured grants of more than RM 2 million from IRPA and other sources for its projects.

 
History
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University of Malaya is among the four public universities (IPTA) in Malaysia conducting pharmacy programmes in Malaysia. The Department of Pharmacy was established in 1995 within the Faculty of Medicine, to cater for the increase need of pharmacists for the public healthcare system.

Since the year 2000, the department is housed in the Pharmacy and Allied Health Sciences Building, Faculty of Medicine. There are about 30 members of full-time staff, over 200 undergraduates and a very active Pharmacy Student Society.

Past and present Heads of the Department of Pharmacy

1995 – 1997 Professor Dr. Yeoh Peng Nam
1997 – 2001 Associate Professor Dr. Hadida Hashim
2001 – 2004 Associate Professor Dr. Hjh Samsinah Hj Hussain
2004 – 2006 Associate Professor Dr. Chung Lip Yong
April 2006 – August 2006 Associate Professor Dr. Hjh Samsinah Hj Hussain
2006 – 2014 Associate Professor Dr. Mohamed Ibrahim Noordin
2014 – Present Associate Professor Datin Dr. Zoriah Aziz
 
Staff
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Academic Programme
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Undergraduate Programme:

A four year Bachelor of Pharmacy (B. Pharm. (Hons)) course under semester system is offered to Malaysian undergraduates. The undergraduate programme consists of 44 core pharmacy modules under five disciplines, Pharmaceutical Chemistry, Scientific Basis of Therapeutics, Pharmaceutical Technology, Clinical Pharmacy and Pharmacy Practice.

Postgraduate Programme:

Postgraduate programmes by research leading to MSc and PhD degrees are offered to both qualified Malaysian and overseas students. The research programmes encompass various areas of pharmaceutical sciences, including medicinal chemistry, natural products chemistry, drug action, drug delivery, pharmacoenconomics, pharmacoepidemiology and evidence based pharmacotherapy related to clinical and pharmacy practice.

To support these activities, the department is equipped with state-of-the-art research tools for biological chemistry, analytical chemistry and formulation research such as a pharmaceutical pilot plant facility for scale up experimental production of tablets and capsules, and microplate scintillation and luminescence counter, cell harvester and robotic liquid handling system for medium and high throughput biomolecular assays. These facilities are supplemented through collaborative work with researchers in other departments and faculties at the University of Malaya (UM), the Forest Research Institute Malaysia (FRIM), the Forest Research Center (FRC), Universiti Kebangsaan Malaysia (UKM), Universiti Putra Malaysia (UPM), and the pharmaceutical industry.

The research projects conducted at the Department are largely funded by grants from University of Malaya, the Intensification of Research in Priority Areas (IRPA) and pharmaceutical companies. To date the Department has successfully secured grants of more than RM 2 million from IRPA and other sources for its projects.

 
Research
...

Postgraduate programmes by research leading to MSc and PhD degrees are offered to both qualified Malaysian and overseas students. The research programmes encompass various areas of pharmaceutical sciences, including medicinal chemistry, natural products chemistry, drug action, drug delivery, pharmacoenconomics, pharmacoepidemiology and evidence based pharmacotherapy related to clinical and pharmacy practice.

To support these activities, the department is equipped with state-of-the-art research tools for biological chemistry, analytical chemistry and formulation research such as a pharmaceutical pilot plant facility for scale up experimental production of tablets and capsules, and microplate scintillation and luminescence counter, cell harvester and robotic liquid handling system for medium and high throughput biomolecular assays.

These facilities are supplemented through collaborative work with researchers in other departments and faculties at the University of Malaya (UM), the Forest Research Institute Malaysia (FRIM), the Forest Research Center (FRC), Universiti Kebangsaan Malaysia (UKM), Universiti Putra Malaysia (UPM), and the pharmaceutical industry. The research projects conducted at the Department are largely funded by grants from University of Malaya, the Intensification of Research in Priority Areas (IRPA) and pharmaceutical companies. To date the Department has successfully secured grants of more than RM 2 million from IRPA and other sources for its projects.

List of Research Projects in 2009

 

No.

Research Title Researchers/ Co-Principal Co-Researcher(s) / Supervisor(s)

1.

Prevalence and risk factors of asthma, chronic obstructive disease (COPD) and obstructive sleep apnea (OSA) in Malaysia

Samsinah Hj Hussain  

2.

Optimisation and characterisation of insulin encapsulation by a new polymer, carboxymethylatedkappa-carrageenan

Chung Lip Yong Mohamed Ibrahim Noordin

3.

Isolation and characterisation of lipoxygenase inhibitory compounds from Malaysian plants by using optimized lipoxygenase assay

Chan Kit Yee Chung Lip Yong, Khalit Mohamad

4.

Characterisation of anti-inflammatory profiles of synthesised flavonoids and their precursors

Audrey Ooi Joo Ann Chung Lip Yong, Michael Buckle

5.

Self targetting novel polymeric drug conjugate delivery system for cancer treatment

Ernidila Ramli Chung Lip Yong

6.

Development of robust pharmaceutical base for microemulsion using palm oil

Hussam S Basheer Mohamed Ibrahim Noordin

7.

Development of semi-solid pharmaceutical bases from palm oil and palm kernel oil blends

Laith N Zaki Mohamed Ibrahim Noordin

8.

Chemical constituents and their antitumour activity of two Chisocheton species; Chisocheton ceramicus and Chisocheton erythrocarpus

Khalit Mohamad  

9.

Identification of barriers in the use of medications by the visually impaired community. Provide solution to the problems

Lee Hong Gee  

10.

Synthesis and investigation of the structure-activity relationships of some muscarinic active flavonoid compounds

Michael Buckle Chung Lip Yong, Noorsaadah Abd. Rahman

11.

Structure-based design and synthesis of muscarinic receptor active compounds as potential therapeutic drugs

Michael Buckle Chung Lip Yong, Noorsaadah Abd. Rahman

12.

Rational design and synthesis of aporphinoids with dopamine and 5-hydroxytryptamine receptor activity

Michael Buckle Chung Lip Yong, Noorsaadah Abd. Rahman

13.

Application of palm oil derivatives for preparation of liposomal doxorubicin as anticancer drug delivery system

Mohamed Ibrahim Noordin Hamid Akbari Javar

14.

Medication adherence of patients with chronic disease

Chua Siew Siang  

15.

A pharmaceutical care model for the management of diabetic patients

Chua Siew Siang  

16.

Modified carrageenan with acid resistant capability

Chung Lip Yong  

17.

Smoking cessation program

Faizah Safina
 
Services
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The Department conducts consultancy services project basis.

Facilities at the Department of Pharmacy
The Department is equipped with state of the art tools and equipment for teaching, research and provide consultancy in the areas of biological and analytical chemistry, natural products and solid dosage forms.

Pharmaceutical Pilot Plant

The Pharmaceutical Pilot Plant of the Department of Pharmacy, is the first of its kind and capacity to in South East Asia, available in a teaching institution. Build and operated in accordance to cGMP, the customized equipment have a capacity to handle 20kg to 60kg batches sizes of ingredients and powders. The plant is capable of producing 70,000 tablets and 30,000 capsule per hour.

A complete range of equipment to carry tests In Process Quality Control (IPQC) and Quality Control (QC) of the products are also available.The Department has also laboratory scale equipment to do preliminary R&D formulation before scaling up to the industrial level at the Pilot Plant.

GPCR Screening Facilities 

The search for therapeutic agents acting via G-protein coupled receptors (GPCRs) has proved to be highly successful and it is estimated that over 55% of all modern drugs are targeted at GPCRs. It is expected this will continue to be a fertile area of pharmaceutical research. The staff and postgraduate students are actively involved in the search of potential receptor active constituents from natural products using competitive receptor binding techniques. The laboratory is equipped with TopCount NXT microplate reader, fluorescence microplate reader, FilterMate cell harvester, MultiProbe II automated liquid handling system, microplate washer and reagent dispensers, cell culture facility, chromatography facility, etc. Recent findings include identification several novel muscarinic receptor modulators and anti-methicillin resistant Staphylococcus aureus compounds.To complement this, the group is also involved in the design of novel systemic and oral polymeric delivery systems for therapeutic agents.

 
Future Plan
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In tandem with the role of pharmacist as a member of the healthcare team, the Department of Pharmacy is currently reviewing and revamping the curriculum. This is to ensure that the graduates that we produce are effectively playing their role as experts on all aspects of medicines whether they work in hospitals (eg. in primary care), industry (eg. research), government agencies (eg. regulatory affairs), community pharmacies or universities.

Last Updated: 29/11/2018