Research

List of Projects

Principal Investigator Title of Project
Prof. Dr. Cheah Phaik Leng
  1. Cell-cycle regulators in hepatocellular carcinoma
  2. p161NK4a as a surrogate marker for high-risk HPV to improve diagnostic accuracy and add prognostic value to the histopathological diagnosis of cervical neoplasia
Prof. Datuk Dr. Looi Lai Meng An investigation into the clinical utility of serum telomerase as a molecular detection marker for breast cancer
Prof. Dr. Wong Kum Thong
1. Pathology of Infectious diseases
  1. Human viral encephalitis including Henipavirus encephalitis, rabies, Japanese encephalitis and Enterovirus 71 encephalomyelitis
  2. Animal models of henipavirus and Enterovirus 71 infections
  3. Melioidosis (Burkholderia pseudomallei infection in humans and animal model)
  4. Plasmodium knowlesi (monkey) malaria
  5. In situ hybridization techniques in the detection of pathogens in infected tissues
  6. Dengue and cellular targets

2.   Pathology of muscle disease

  1. Genetics of inherited muscle diseases: Limb girdle muscular dystrophy (e.g. dysferlinopathy,
    sarcoglycanopathy), Ullrich congenital
    muscular dystrophy
  2. Inflammatory myopathy
Associate Prof Dr. Veera Sekaran Nadarajan
  1. Characterisation of tyrosine kinase domain mutations in patients with chronic myeloid leukemia with resistance to imatinib therapy and implication on cell cycling and apoptotic pathways
  2. Identification of mutations other than JAK2 V617F in patients with myeloproliferative neoplasm and correlation with their phenotype and clinical outcome
  3.  Serial identification of unbalanced genomic aberrations by array CGH in patients with chronic myeloid leukemia on imatinib therapy
Associate Prof Dr. Malathi A/P Thevarajah Clinical Utility of Her-2/neu as a Tumor Marker for monitoring women with breast cancer in the Malaysian population
Associate Prof Dr.Pavai Sthaneshwar Establishment of reference interval for newborn screening by Tandem mass spectrometry
Dr. Hemalatha Shanmugam
  1. Diagnostic usefulness and application of rapid screening test for pregnant female alpha thalassaemia carriers
  2. Assessment and clinical utility of immature platelet function (IPF) in immune and non-immune thrombocytopenias
Dr. S.Jayaranee
  1. Frequency of von Willebrand’s disease(vWD) in women presenting with presumed dysfunctional uterine bleeding in Universit Malaya Medical Centre
  2. Prevalence and clinical importance of antiphospholipid antibodies in systemic lupus erythematosus patients in the Malaysian population