Research

Paediatric Cardiology Unit

  1. QUALITY OF LIFE ASSESSMENT IN CHILDREN WITH CONGENITAL HEART DISEASE : A COMPARATIVE STUDY BETWEEN PATIENTS AND CONTROLS, Co-Investigator, 2013-2014, NONE; AH Lee
  2. QUALITY OF LIFE ASSESSMENT IN CHILDREN WITH CONGENITAL HEART DISEASE : A COMPARATIVE STUDY BETWEEN PATIENTS AND CONTROLS, Co-Investigator, 2013-2014, NONE; O Asma
  3. Congenital Heart Diseases in Adults, Co-Investigator, 2008; O Asma
  4. Congenital Heart Diseases in Children, Co-Investigator, 2008; O Asma
  5. Kawasaki Disease, Long Term Outcome, Co-Investigator, 2008; O Asma
  6. Rheumatic Heart Disease and Acute Rheumatic Fever, Its Prevalence and Long Term Outcome, Co-Investigator, 2008; O Asma
  7. CHILDHOOD OBESITY AND METABOLIC SYNDROME IN SECONDARY SCHOOL CHILDREN IN KLANG VELLEY, MALAYSIA, Co-Investigator, 2010-2011, Short Term Research Fund (Vote F)(PJP), National; Z Norazah
  8. Long term outcome of patients with repaired congenital heart disease.

 Paediatric Community Unit

  1. Magnetic resonance and diffusion tensor imaging features of hypoxic ischemic encephalopathy in white matter maturation of developmental milestones in childhood, Co-Investigator, 2013-2015, Geran Penyelidikan Universiti Malaya (UMRG), National; J Subhashini
  2. A Multicenter Randomized Controlled Trial of Therapeutic Hypothermia plus Magnesium Sulphate (MgSO4) vs. Therapeutic Hypothermia plus Placebo in the management of Term babies with Hypoxic Ischemic Encephalopathy (The Mag Cool Study), Co-Investigator, 2012-2014, Hamad Medical Corporation, Qatar, International; J Subhashini
  3. Patterns of injury presenting to a Paediatric Trauma and Emergency Unit in a tertiary hospital in Malaysia, Principal Investigator(PI), 2012-2014, Postgraduate Research Grant(PPP), National; A Sharifah Aida
  4. Patterns of injury presenting to a Paediatric Trauma and Emergency Unit in a tertiary hospital in Malaysia, Co-Investigator, 2012-2014, Postgraduate Research Grant(PPP), National; Knowledge, Attitude and Perception on Secondhand Smoke among pregnant mothers, parents and university students who are non-smokers, Co-Investigator, 2012-2013, UMCAS, National; JM Mary
  5. Use of Social Networking Sites by Adolescents and Relationship to Online Victimisation, Principal Investigator(PI), 2012-2014, Geran Penyelidikan Universiti Malaya (UMRG), National; Knowledge, Attitude and Perception on Secondhand Smoke among pregnant mothers, parents and university students who are non-smokers, Co-Investigator, 2012-2013, UMCAS, National; JM Mary
  6. Elucidation of The Mechanism and Rescue of the Human Neural Tube Defects Gene(s), Co-Investigator, 2012-2014, HIR; JM Mary
  7. Parental Perception of Pain in Nonverbal Children with Cerebral Palsy, Principal Investigator(PI), 2012-2013, BKP, National; J Subhashini
  8. Parental Perception of Pain in Nonverbal Children with Cerebral Palsy, Co-Investigator, 2012-2013, BKP, National; JM Mary
  9. Knowledge, Attitude and Perception on Secondhand Smoke among pregnant mothers, parents and university students who are non-smokers, Co-Investigator, 2012-2013, UMCAS, National; A Sharifah Aida
  10. Investigating EphA2 phosphorylation and signalling mechanism in adhesion and fusion of the spinal neural tube, Co-Investigator, 2011-2015, HIR; JM Mary
  11. Is the leading edge of neurulation an asymmetrical lamellipodia-like structure emanating from the surface ectoderm and whether this mirrors the human spina bifida condition?, Co-Investigator, 2010-2013, HIR; JM Mary
  12. Awareness and communication practice of parents on primary school children on sexual abuse in Selangor, Co-Investigator, 2009-2011, Geran Penyelidikan Universiti Malaya (UMRG), National; JM Mary
  13. Use of Information and Communication Audio-Visual Technology by Minors: Exposure to risks and victimisation, Principal Investigator(PI), 2009-2011, Geran Penyelidikan Universiti Malaya (UMRG), National; JM Mary
  14. Service Providers and Public Perception of Child Abuse & Neglect: When is it necessary to intervene?, Co-Investigator, 2008-2009, Short Term Research Fund (Vote F)(PJP), National; JM Mary
  15. Non-accidental head injuries in children, Principal Investigator(PI), 2008; JM Mary
  16. Child abuse, Co-Investigator, 2008; JM Mary
  17. Child sexual abuse, Co-Investigator, 2008; JM Mary
  18. Are Malaysian teachers ready to assume the duties of reporting child abuse and neglect.

Paediatric Endocrinology Unit

  1. Obesity in Malaysian adolescent population: Prevalence, risk factors, complications and intervention, Co-Investigator, 2013-2015, HIR; J Muhammad Yazid
  2. My Body is Fit and Fabulous: An Intervention Programme to Combat Obesity among Malaysian School Children (MyBFF@SCHOOL), Co-Investigator, 2013-2015, Ministry of Health, Malaysia, National J Muhammad Yazid
  3. Socio-economic inequality in presence of cardiovascular risk among adolescents, Principal Investigator(PI), 2013-2014, Geran Penyelidikan Universiti Malaya (UMRG), National; J Muhammad Yazid
  4. A Phase III, Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of MK-0431A (A Fixed-Dose Combination Tablet of Sitagliptin and Metformin) in Pediatric Patients with Type 2 Diabetes Mellitus, Principal Investigator(PI), 2012-2018, Company Sponsored Research (MSD), International; J Muhammad Yazid
  5. A Phase III, Multicenter, Double- Blind, Randomized, Placebo- and Metformin-Controlled Clinical Trial to Evaluate the Safety and Efficacy of Sitagliptin in Pediatric Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control, Principal Investigator(PI), 2012-2018, Company Sponsored Research (MSD), International; J Muhammad Yazid
  6. A Phase III, Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of MK-0431A (A Fixed-Dose Combination Tablet of Sitagliptin and Metformin) in Pediatric Patients with Type 2 Diabetes Mellitus, Co-Investigator, 2012-2018, Company Sponsored Research (MSD), International; H Fatimah
  7. A Phase III, Multicenter, Double- Blind, Randomized, Placebo- and Metformin-Controlled Clinical Trial to Evaluate the Safety and Efficacy of Sitagliptin in Pediatric Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control, Co-Investigator, 2012-2018, Company Sponsored Research (MSD), International; H Fatimah
  8. Risk factor for Chronic Non- Communicable Diseases Adolescents- Malaysian Health and Adolescents Longitudinal Research Study (MyHEARTS), Co-Investigator, 2012-2013, Geran Penyelidikan Universiti Malaya (UMRG), National; J Muhammad Yazid
  9. Hypovitaminosis D in Malaysian Overweight/Obese Adolescents: Its Relationship with Adiposity, Insulin Sensitivity, Metabolic Risk Factors, and Adiponectin, Principal Investigator(PI), 2011-2013, Geran Penyelidikan Universiti Malaya (UMRG), National; J Muhammad Yazid
  10. Hypovitaminosis D in Malaysian Overweight/Obese Adolescents: Its Relationship with Adiposity, Insulin Sensitivity, Metabolic Risk Factors, and Adiponectin, Co-Investigator, 2011-2013, Geran Penyelidikan Universiti Malaya (UMRG), National; H Fatimah
  11. Identification of Predictors for Dosing Determination of Metformin in Obese Children/Adolescents, Co-Investigator, 2011-2013, Geran Penyelidikan Universiti Malaya (UMRG), National; H Fatimah
  12. Risk factor for Chronic Non- Communicable Diseases Adolescents- Malaysian Health and Adolescents Longitudinal Research Study (MyHEARTS), Co-Investigator, 2011-2012, Short Term Research Fund (Vote F)(PJP), National; J Muhammad Yazid
  13. The Role of Various Genetic Polymorphism in Obesity, Co-Investigator, 2011-2012, Short Term Research Fund (Vote F)(PJP), National; J Muhammad Yazid
  14. The role of various Genetic Polymorphisms in Childhood Obesity, Co-Investigator, 2011-2012, Geran Penyelidikan Universiti Malaya (UMRG), National; J Muhammad Yazid
  15. Hypovitaminosis D in Malaysian Overweight/Obese Adolescents: Its Relationship with Adiposity, Insulin Sensitivity, Metabolic Risk Factors, and Adiponectin, Co-Investigator, 2011-2012, Geran Penyelidikan Universiti Malaya (UMRG), National; S Nurshadia
  16. CHILDHOOD OBESITY AND METABOLIC SYNDROME IN SECONDARY SCHOOL CHILDREN IN KLANG VELLEY, MALAYSIA, Co-Investigator, 2010-2011, Short Term Research Fund (Vote F)(PJP), National: H Fatimah
  17. CHILDHOOD OBESITY AND METABOLIC SYNDROME IN SECONDARY SCHOOL CHILDREN IN KLANG VELLEY, MALAYSIA, Co-Investigator, 2010-2011, Short Term Research Fund (Vote F)(PJP), National: CHILDHOOD OBESITY AND METABOLIC SYNDROME IN SECONDARY SCHOOL CHILDREN IN KLANG VELLEY, MALAYSIA, Co-Investigator, 2010-2011, Short Term Research Fund (Vote F)(PJP), National; J Muhammad Yazid
  18. Carotid artery intima media thickness (IMT) in obese children seen in UMMC in relation to their respective BMI (age-specific), Principal Investigator(PI), 2008-2009, , University; AZ Azriyanti
  19. Carotid artery intima media thickness (IMT) in obese children seen in UMMC in relation to their respective BMI (age-specific), Co-Investigator, 2008-2009, , University; H Fatimah
  20. Mutation analysis of genes invovled in growth disorders, Co-Researcher, 2008-2009, Short Term Research Fund (Vote F)(PJP), National; H Fatimah
  21. A study on the relationship between fatty liver changes on ultrasound and the sverity of BMI in overweight and obese children., Co-Investigator, 2008-2009, Short Term Research Fund (Vote F)(PJP), National; H Fatimah
  22. A study on the relationship between fatty liver changes on ultrasound and the sverity of BMI in overweight and obese children., Co-Investigator, 2008-2009, Short Term Research Fund (Vote F)(PJP), National; AZ Azriyanti
  23. Childhood diabetes, Co-Investigator, 2008; J Muhammad Yazid
  24. Malaysia Outcome Research of Children and Adolescents with Diabetes mellitus (M.O.R.A.D), Co-Investigator, 2006-2020, Ministry of Health, NationalJ Muhammad Yazid
  25. Detection of Familial Hypercholesterolemia gene mutation amongst the Malaysian population, Co-Investigator, 2006-2012, MOSTI; H Fatimah
  26. Validation of Bahasa Melayu Version of The Summary of Diabetes Self Care Activities (SDSCA), Principal Investigator(PI), 2006-2008, Ministry of Health, National; J Muhammad Yazid
  27. Factors associated with child growth and school performance among primary school children in Selangor, Malaysia, Co-Investigator, 2001-2004, Center of Economic Devt and Ethic Relations, Univ Malaya, National: H Fatimah
  28. Hypovitaminosis D in Malaysian Overweight/Obese Adolescents: Its Relationship with Adiposity, Insulin Sensitivity, Metabolic Risk Factors, and Adiponectin; J Muhammad Yazid
  29. Risk Factors for Chronic Non-Communicable Diseases among Adolescents Malaysian Health and Adolescents longitudinal Research Team Study (MyHEARTS); J Muhammad Yazid
  30. THE ROLE OF VARIOUS GENETIC POLYMORPHISMS IN CHILDHOOD OBESITY; J Muhammad Yazid
  31. Childhood obesity and Metabolic Syndrome in secondary school children in Klang Valley, Malaysia;J Muhammad Yazid

Paediatric Gastroenterology, Hepatology and Nutrition Unit

  1. Stool Colour Card for Newborn Infants with Cholestasis, Co-Investigator, 2012-2014, Geran Penyelidikan Universiti Malaya (UMRG), National; WS Lee
  2. Pulse Oximetry Screening for Critical Congenital Heart Defects in Apparently Well Term Newborns, Co-Investigator, 2012-2013, Geran Penyelidikan Universiti Malaya (UMRG), National; WS Lee
  3. Analysis of DLG5 Genetic Polymorphisms in Malaysian Crohn Disease (CD) Patients, Principal Investigator(PI), 2010, Geran Penyelidikan Universiti Malaya (UMRG), National; WS Lee
  4. A Randomised, Double Blind, Controlled Study on the Effect of a Growing up Milk on the Occurrence of Infections in Toddlers (GIANT), Principal Investigator(PI), 2009-2010, Danone Research, the Netherlands, International: WS Lee
  5. Prospective, Two-Centre, Surveillance Study of Rotavirus Disease in UMMC, Kuala Lumpur, and Hospital Kuala Trengganu, Trengganu., Principal Investigator(PI), 2008-2010, Centre for Disease Control and Prevention, Atlanta, United States, International; WS Lee
  6. Prevalence and Correlates of Depressive Symptomatology among School Children and Children with Chronic Disease in Malaysia, Principal Investigator(PI), 2008-2010, Short Term Research Fund (Vote F)(PJP), National; CM Christopher Boey
  7. Chronic Inflammatory Bowel Disease – data collection UMMC patient since 2006.
  8. Neonatal Cholestasis: perspective from a tertiary centre in Malaysia, PROJECT LEADER, 1998-2005, Short Term Research Fund (Vote F)(PJP), National; WS Lee
  9. Rotavirus and acute diarrhea
  10. Chronic diarrhea in children
  11. The yield of endoscopy in children with bleeding
  12. Autoimmune hepatitis
  13. Role of HIDA scanning in biliary atresia
  14. Recurrent abdominal pain in children
  15. Psychosocial factors, educational attainment in children with gastrointestinal complaints
  16. Gastrointestinal complaints in children with oncological / haematological conditions undergoing chemotherapy – the role of endoscopy
  17. MNF116 immunohistochemistry of the liver and biliary tree for biliary atresia and other cholestatic disorders in infancy.
  18. Database Paediatric Gastroenterology and Hepatology (Chai Pei Fan).
  19. Association of the inflammatory bowel disease (IBD5) and Interleukin-23 receptor (IL23R) genetic polymorphisms in Malaysian patients with Crohn’s disease
  20. Genotypes in Malaysia and universal rotavirus vaccination.
  21. Impact on parents during hospitalization for severe acute gastroenteritis in young children
  22. Acute Infectious Diarrhea Lessons Learned From the Past?

Paediatric Genetic Unit

  1. Malaysian registry for children with tuberous sclerosis complex (TSC), Co-Investigator, 2013-2014, Novartis (M) Sdn Bhd, National; MK Thong
  2. Elucidation of The Mechanism and Rescue of the Human Neural Tube Defects Gene(s), Co-Investigator, 2012-2014, HIR; MK Thong
  3. Investigating EphA2 phosphorylation and signalling mechanism in adhesion and fusion of the spinal neural tube, Co-Investigator, 2011-2015, HIR; MK Thong
  4. Study of micro ribonucleic acid (miRNA) patterns and messesnger RNA splicingamong myotonic dystrophy (RM1) patients of different ages and clinical features., Principal Investigator(PI), 2010-2012, Fundamental Research Grant Scheme (FRGS), National; MK Thong
  5. Is the leading edge of neurulation an asymmetrical lamellipodia-like structure emanating from the surface ectoderm and whether this mirrors the human spina bifida condition?, Co-Investigator, 2010-2013, HIR; MK Thong
  6. Inborn errors of metabolism: a clinical and laboratory evaluation in acutely ill paediatric patients, Co-Investigator, 2009-2010, Geran Penyelidikan Universiti Malaya (UMRG), University; MK Thong
  7. Confirmation of myotonic dystrophy among Malaysian patients., Principal Investigator(PI), 2008-2009, Short Term Research Fund (Vote F)(PJP), National; MK Thong
  8. Resolution Genome-wide Array Analysis In Unexplained Syndromic Patients with Normal Karyotype (2008-2009;Malaysia Medical Institute, Ministry of Health, and UKM; Thong Meow Keong).
  9. Biochemical Studies on Galactosaemia in Malaysia (2008-2009;Malaysia Medical Institute, Ministry of Health, and UKM; Thong Meow Keong).
  10. Problem based learning, Co-Investigator, 2008; MK Thong
  11. Genetic counselling, Co-Investigator, 2008; MK Thong
  12. Inherited metabolic disorders, Co-Investigator, 2008; MK Thong
  13. Collaborative project between University of Malaya and Cancer Research Initiatives Foundation (CARIF) 2007-2012. A Multi-Pronged Tackle of Three Cancers Relevant to Malaysians: Searching for the Presence of Predisposition Genes, Mutation Screening for Predisposition Genes for Risk Assessment for Breast, Oral and Nasopharyngeal Cancers., Co-Investigator, 2007-2012, IRPA, International; MK Thong
  14. Detection of Familial Hypercholesterolemia gene mutation amongst the Malaysian population, Co-Investigator, 2006-2012, MOSTI; MK Thong
  15. “Epidemiology and prevention of major birth defects in the Kinta district, Perak, Malaysia” under intensified Research in Priority Areas in Malaysia, collaborative study with Ministry of Health, Malaysia.Principal Investigator(PI), 2002-2005, IRPA, National; MK Thong
  16. Study of micro ribonucleic acid (miRNA) patterns and messesnger RNA splicingamong myotonic dystrophy (RM1) patients of different ages and clinical features. Principal Investigator(PI); (Mohd Taufik Ishak, Cik Kathlin Ambrose);Fundamental Research Grant Scheme (FRGS/1/10/SP/UM/01/16); RM100,000; MK Thong (ANNUAL REPORT 2012)
  17. Study of Uniparental Disomy (UPD) and Genomic Imprinting among Patients with Beckwith- Wiedemann Syndrome and Russell-Silver Syndrome in Malaysia”; Principal Investigator(PI); (Mohd Taufik Ishak); UMRG grant RG427/12HTM; HB Chew (ANNUAL REPORT 2012)
  18. Study of Uniparental Disomy (UPD) and Genomic Imprinting among Patients with Beckwith- Wiedemann Syndrome and Russell-Silver Syndrome in Malaysia”; Co-Investigator(PI); (Mohd Taufik Ishak); UMRG grant RG427/12HTM; MK Thong (ANNUAL REPORT 2012)
  19. Adult-onset Genetics; MK Thong
  20. Birth Defects and Dysmorphology; MK Thong
  21. Database in syndromic and dysmorphic children; MK Thong
  22. Polymerase Chain Reaction Analyses of Malaysian Patients with Myotonic Dystrophy (University Malaya grant Vote F No. F0176/2007B; Thong Meow Keong)
  23. A Multi-Pronged Tackle of Three Cancers Relevant to Malaysians: Searching for the Presence of Predisposition Genes, Mutation Screening for Predisposition Genes for Risk Assessment and Exploring New Anti-Cancer Therapy for Oral, Nasopharyngeal and Breast Cancers (Grant MOSTI: 06-00-000 & University Malaya; Thong Meow Keong).
  24. Determination of the genetic mutations in muscular dystrophy and mitochondrial encephalomyopathy in the multiethnic Malaysian population and their correlation with clinical features (Science Fund Cycle 1/2007 No. 12-02-03-2038; Thong Meow keong).

Paediatric Immunology and Infectious Disease Unit

  1. Cellular responses in HFMD among Malaysian children less than 12 years old., Co-Investigator, 2012-2014, NONE; MT Koh
  2. A STUDY TO INVESTIGATE THE DISEASE MECHANISMS OF SEVERE DENGUE, Co-Investigator, 2012-2014, LRGS; R Hannah Wardiah
  3. Safety And immunogenicity of A Tetravalent Dengue vaccine in Healthy Children Aged 2 To 11 Years in Malaysia (CYD32) ClinicalTrials.gov Identifier: NCT01254422, Principal Investigator(PI), 2012-2012, Sanofi Pasteur, Lyon, France, International; MT Koh
  4. A prospective, open-label, non-comparative study to assess the safety, tolerability and efficacy of voriconazole for the primary and salvage treatment of invasive candidiasis, candidemia, and esophageal candidiasis in pediatric subjects. Protocol A1501085 ClinicalTrials.gov Identifier: NCT01092832, Principal Investigator(PI), 2011-2014, Pfizer, International; MT Koh
  5. Study of a tetravalent dengue vaccine in healthy children aged 2 to 11 year old in Malaysia, Co-Investigator, 2011-2013, Sanofi Aventis, International; R Hannah Wardiah
  6. The Role of Triggering Receptors Expressed on Myeloid Cells (TREM) Receptors and Toll-like Receptors (TLRs) In Patients With Bacterial Sepsis., Co-Investigator, 2011-2013, Geran Penyelidikan Universiti Malaya (UMRG), National; MT Koh
  7. A Prospective, Randomised Trial Comparing The Safety, Tolerability and Efficacy of Voriconazole And Anidulafungin In Combination To That Of Voriconazole Alone When used For Treatment of Primary Therapy of Invasive Aspergillosis in Paediatric Subjects Aged 2 To 17 Years. Protocol A1501095, Principal Investigator(PI), 2011-2013, Pfizer Pharmaceutical Inc, New York, USA, International; MT Koh
  8. The role of Macrophage Activation Syndrome/Haemophagocytic Syndrome in Dengue, Co-Investigator, 2011-2013, Postgraduate Research Grant(PPP), Nationa; MT Kohl
  9. A Prospective, Open-label, Non-comparative Study to Assess The Safety, Tolerability And Efficacy of Voriconazole and Its Salvage Treatment of Invasive Candidiasis, Candidemia, and Eosphageal Candidiasis in Paediatric Subjects A1501085, Principal Investigator(PI), 2010-2014, Pfizer Pharmaceutical Inc. New York, USA, International; MT Koh
  10. Safety and Immunogenicity of a Tetravalent Dengue vaccine in Healthy Children Aged 2 to 11 Years in Malaysia ClinicalTrials.gov Identifier: NCT01254422, Principal Investigator(PI), 2010-2012, SanoPasteur, Lyon, France, International; MT Koh
  11. A Comparative Study to Evaluate the Impact of Pneumococcal Vaccination on Nasopharyngeal Carriage Among Children Vaccinated with PHiD-CV compared to a Pneumococcal vaccine Naive Control Group, Principal Investigator(PI), 2010-2011, Unconditional Grant from GlaxoSmithKline Pharmaceuticals (M), National; MT Koh
  12. A Phase III multicentre, double-blind, randomised study to assess the non-inferiority of a commercial lot of GlaxoSmithKline (GSK) Biologicals’ 10-valent pneumococcal conjugate (10PN-PD-DiT)vaccine compared to a clinical Phase III vaccine lot, when given as a three-dose primary immunisation course. ClinicalTrials.gov identifier: NCT00808444, Principal Investigator(PI), 2009-2010, GlaxoSmithKline Biologicals, Belgium, International; MT Koh
  13. Assessment of the nutritional status of children with HIV receiving antiretroviral medication, Co-Investigator, 2008-2009, United Nations Development Programme (UNDP) For UNAIDS, National; MT Koh
  14. Population pharmocokinetics of gentamicin, amikacin, and vancomycin in paediatric patients at the University of Malaya Medical Centre, Co-Investigator, 2008-2009, Own research fund from previous industrial research, University; MT Koh
  15. Epidemiological studies on ID, Principal Investigator(PI), 2008; MT Koh
  16. Paediatric HIV / AIDS, Principal Investigator(PI), 2008; MT Koh
  17. Paediatric infectious diseases, Principal Investigator(PI), 2008; MT Koh
  18. Tuberculosis, Principal Investigator(PI), 2008; MT Koh
  19. Vaccinology, Principal Investigator(PI), 2008; MT Koh
  20. Communicable diseases, Principal Investigator(PI), 2008; MT Koh
  21. Clinical Immunology, Co-Investigator, 2008; MT Koh
  22. Clinical trials – vaccines and anti-microbials, Co-Investigator, 2008; MT Koh
  23. A One-Year Prospective Study of Invasive Pneumococcal Disease in Hospitalised Malaysian Children, Co-Investigator, 2007-2009, ScienceFund, National; MT Koh
  24. A Prospective, multicenter, double-blind, randomised comparative study to evaluate safety, local tolerability and clinical outcome of Ertapenem sodium (MK-0826) versus Ceftriaxone sodium in pediatric patients with complicated urinary tract infection, skin and soft tissue infection or community-acquired pneumonia. Protocol 036-01. ClinicalTrials.gov identifier: NCT00451386., Principal
    Investigator(PI), 2005-2006, Merck & Co. Inc, USA, International; MT Koh
  25. “Phase III Clinical Trial on Safety and Immunogenicity of Tetravalent Dengue Vaccine in Malaysian Children”; MT Koh (ANNUAL REPORT 2012)
  26. “A Cross Sectional Study To Assess Bordetella pertussis Infection Among Adolescents and Adults With prolonged Cough In Malaysia, Philippines, Taiwan and Thailand”.; MT Koh (ANNUAL REPORT 2012)
  27. “A Cross Sectional Study To Assess Bordetella pertussis Infection Among Adolescents and Adults With prolonged Cough In Malaysia, Philippines, Taiwan and Thailand”; R Hannah Wardiah
  28. “Cellular Response IN Hand, Foot And Mouth Disease Among Malaysian Children Less Than 12 Years Old”; MT Koh (ANNUAL REPORT 2012)
  29. “Cellular Response IN Hand, Foot And Mouth Disease Among Malaysian Children Less Than 12 Years Old”; R Hannah Wardiah

Paediatric Intensive Care Unit

  1. Magnetic resonance and diffusion tensor imaging features of hypoxic ischemic encephalopathy in white matter maturation of developmental milestones in childhood, Principal Investigator(PI), 2013-2015, Geran Penyelidikan Universiti Malaya (UMRG), National; LL Chai See
  2. A Multicenter Randomized Controlled Trial of Therapeutic Hypothermia plus Magnesium Sulphate (MgSO4) vs. Therapeutic Hypothermia plus Placebo in the management of Term babies with Hypoxic Ischemic Encephalopathy (The Mag Cool Study), Principal Investigator(PI), 2012-2014, Hamad Medical Corporation, Qatar, International; LL Chai See
  3. A Multicenter Randomized Controlled Trial of Therapeutic Hypothermia plus Magnesium Sulphate (MgSO4) vs. Therapeutic Hypothermia plus Placebo in the management of Term babies with Hypoxic Ischemic Encephalopathy (The Mag Cool Study), Co-Investigator, 2012-2014, Hamad Medical Corporation, Qatar, International; CS Gan
  4. Clinical evaluation of dengue and identification of risk factors for severe disease: a multicentre study in 6 countries, Principal Investigator(PI), 2011-2015, Oxford University, European Union, International; LL Chai See
  5. A Multicentre Study To Validate The Predictive Value Of Warning Signs In Dengue, Co-Investigator, 2011-2011, WHO, International; LL Chai See
  6. Inborn errors of metabolism: a clinical and laboratory evaluation in acutely ill paediatric patients, Principal Investigator(PI), 2009-2010, Geran Penyelidikan Universiti Malaya (UMRG), University; CS Gan (ANNUAL REPORT 2012)
  7. Inborn errors of metabolism: a clinical and laboratory evaluation in acutely ill paediatric patients, Co-Investigator, 2009-2010, Geran Penyelidikan Universiti Malaya (UMRG), University: CS Gan
  8. Impact of An Intervention on Incidence of Nosocomial Bloodstream Infection in a Pediatric Intensive Care Unit in a middle-income country, Co-Investigator, 2008-2010, University Malaya, National; CS Gan
  9. Intensive Care in the Developing World, Co-Investigator, 2008; LL Chai See
  10. Non-Invasive Ventilation in Children, Co-Investigator, 2008; LL Chai See
  11. Nosocomial Infections in the PICU, Co-Investigator, 2008; LL Chai See
  12. Infectious Diseases – Vaccine Trials, Co-Investigator, 2008; LL Chai See
  13. Improving Outcome in Severe Dengue, Co-Investigator, 2008
  14. Economic Burden of Dengue, Co-Investigator, 2008 ; LL Chai See
  15. Risk Factors for Severe Dengue, Co-Investigator, 2008 : LL Chai See
  16. Clinical Management of Dengue, Co-Investigator, 2008 ; LL Chai See
  17. Dengue, Co-Investigator, 2008; LL Chai See
  18. Hypothermis Therapy for Hypoxic Ischemic Encephalopathy in Newborns ( Emiellyuza Yusnita Alias); CS Gan (ANNUAL REPORT 2012)

Paediatric Neonatology Unit

  1. ESBL and Non-ESBL Colonisers in the Neonatal Unit – Ten year Analysis of Patterns of Emergence, Comparison of Clinical Course, Host Characteristics and Outcome., Principal Investigator(PI), 2013-2014, NONE; AK Azanna
  2. Inter- racial comparison of risk factors in retinopathy of prematurity (ROP) progression in a multi-racial Asian community and identifying the predictive values of growth factors in the development of ROP., Co-Investigator, 2012-2015; AK Azanna
  3. A STUDY OF EFFICACY AND TOLERABILITY OF LEVATIRACETAM (KEPPA) AS MONOTHERAPY IN NEWLY DIAGNOSED CHILDHOOD EPILEPSY, Principal Investigator(PI), 01/09/2010, HIR, 31/08/2011;Geran Penyelidikan Universiti Malaya (UMRG), National; YM Choo

Paediatric Nephrology Unit

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Paediatric Neurology Unit

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Paediatric Oncology/Haematology/Haematopoietic Stem Cell Transplantation Unit

  1. PERIPHERAL NEUROPATHY IN SURVIVORS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA, Co-Investigator, 2012-2014, BKP, National; MA Hany
  2. PERIPHERAL NEUROPATHY IN SURVIVORS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA, Co-Investigator, 2012-2014, BKP, National; K Shekhar
  3. PERIPHERAL NEUROPATHY IN SURVIVORS OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA, Co-Investigator, 2012-2014, BKP, National; A Wan Ariffin
  4. A prospective, open-label, non-comparative study to assess the safety, tolerability and efficacy of voriconazole for the primary and salvage treatment of invasive candidiasis, candidemia, and esophageal candidiasis in pediatric subjects. Protocol A1501085 ClinicalTrials.gov Identifier: NCT01092832, Co-Investigator, 2011-2014, Pfizer, International; A Wan Ariffin
  5. Detection of novel mutations in the CFTR gene among Malaysian patients diagnosed with cystic fibrosis, Co-Investigator, 2011-2012, NONE; MA Hany
  6. MASPORE ALL 2010, Principal Investigator(PI), 2010-2017, NUS, National; MA Hany
  7. MASPORE ALL 2010, Co-Investigator, 2010-2017, NUS, National; A Wan Ariffin
  8. Li-Fraumeni Syndrome/Inherited TP53 mutations in Malaysia, Principal Investigator(PI), 2008-2010, IARC,WHO, MASPHO;High Impact Research (HIR-MOHE) grant, National; MA Hany
  9. Development of a robust chimerism analysis system following stem cell transplantation, Principal Investigator(PI), 2008-2010, MOSTI, National; MA Hany
  10. Population Pharmacokinetic (PK) Modelling of Methotrexate in Pediatric Cancer Patients, Principal Investigator(PI), 2008-2010, Short Term Research Fund (Vote F)(PJP), National; A Wan Ariffin
  11. WT-1 gene in acute myeloid leukemia, Principal Investigator(PI), 2008; MA Hany
  12. Childhood Leukemias, Principal Investigator(PI), 2008; MA Hany
  13. Asparaginyl endopeptidase and childhood cancer, Principal Investigator(PI), 2008; MA Hany
  14. WT-1 gene in acute myeloid leukemia, Coordinator, 2007-2008, MOHE, University; MA Hany
  15. Chimerism analysis techniques following haemopoeitic stem cell transplantation, Principal Investigator(PI), 2008; MA Hany
  16. Expression of TERF-2 and hTERT in childhood acute lymphoblastic leukemia, Coordinator, 2007-2008, MAKNA, University; MA Hany
  17. Asparaginyl endopeptidase in childhood cancer, Principal Investigator(PI), 2007-2008, MOHE, National; MA Hany
  18. MASPORE AML, Principal Investigator(PI), 2007, NUS, National; MA Hany
  19. MASPORE AML, Co-Investigator, 2007, NUS, National ; A Wan Ariffin
  20. Quantitative chimerism analysis using microchip electrophoresis system, Principal Investigator(PI), 2006-2008, MOHE, University; MA Hany
  21. Malaysia-Singapore AML 2006 Study, Principal Investigator(PI), 2006-2008, MOHE, International; MA Hany
  22. Oncogene Fusion Transcripts in Acute Lymphoblastic Leukemia, Principal Investigator(PI), 2005-2008, , University; MA Hany
  23. Chimerism analysis using short tandem repeats, Principal Investigator(PI), 2005-2006, Short Term Research Fund (Vote F)(PJP), University; MA Hany
  24. Malaysia-Singapore Acute Lymphoblastic Leukemia Study, Co-Investigator, 2003-2008, Singapore Cancer Syndicate, AStar, International; MA Hany
  25. Minimal Residual Disease assessment via flow cytometry, Principal Investigator(PI), 2000-2002, MAKNA, University; MA Hany
  26. Germ Cell Tumours audit for paediatrics patient since 15 years ago.
  27. GATA1 mutation detection in children with Down Syndrome Acute Myeloid Leukemia; master project – Lum Su Han
  28. Medical student elective project; Iron Chelation Practice among Paediatric Thalassaemia Patients at UMMC, Blood Transfusion Practice in Paediatric Thalassaemia & Case Series of Reporting by Severe Infections in patiet Thalassemia a UMMC.
  29. Catherer – related Blood Stream Infections in Pediatric Oncology patients : a fire-year Retrospective; Medical master student thesis – Farah Khalid;

Paediatric Respiratory Unit

  1. Patterns of injury presenting to a Paediatric Trauma and Emergency Unit in a tertiary hospital in Malaysia, Co-Investigator, 2012-2014, Postgraduate Research Grant(PPP), National;De B Jessie
  2. Validation of the Bahasa Melayu version of the Paediatric cough questionnaire, Co-Investigator, 2012-2014, NONE; De B Jessie (ANNUAL REPORT 2012)
  3. Recognition of respiratory sounds in children, Co-Investigator, 2012-2013, NONE; De B Jessie (ANNUAL REPORT 2012)
  4. Aetiology of chronic suppurative lung disease in children and its impact on the child and family,single centre,UMMC, Principal Investigator(PI), (Ananthan Muthusamy) 2012-2015, NONE; N Anna Marie (ANNUAL REPORT 2012)
  5. Aetiology of chronic suppurative lung disease in children and its impact on the child and family,single centre,UMMC, Co-Investigator, 2012-2015, NONE; De B Jessie
  6. Detection of novel mutations in the CFTR gene among Malaysian patients diagnosed with cystic fibrosis, Principal Investigator(PI), 2011-2012, NONE; N Anna Marie
  7. Etiology of lower respiratory tract infections in children admitted to UMMC, Co-Investigator, 2011-2012, NONE; De B Jessie (ANNUAL REPORT 2012)
  8. Epidemiology of respiratory viruses in children with asthma, Principal Investigator(PI), 2010-2012, NONE; De B Jessie
  9. Epidemiology of respiratory viruses in children with asthma, Co-Investigator, 2010-2012, NONE; N Anna Marie
  10. Prevalence of Obstructive Sleep Apnoea Syndrome (OSA) in Obese children, Co-Investigator, 2009-2011, Geran Penyelidikan Universiti Malaya (UMRG), National; De B Jessie
  11. Prevalence of Obstructive Sleep Apnoea Syndrome (OSA) in Obese children, Co-Investigator, 2009-2011, Geran Penyelidikan Universiti Malaya (UMRG), National; N Anna Marie
  12. Prevalence of Snoring and Obstructive Sleep Apnoea Syndrome (OSA) in Overweight Children, Co-Investigator, 2009-2011, master student project – Izzurina Bashah; UMRG Geran Penyelidikan Universiti Malaya (UMRG), National; N Anna Marie (ANNUAL REPORT 2012)
  13. Risk of asthma in children delivered via LSCS, Principal Investigator(PI), 2009-2011, Geran Penyelidikan Universiti Malaya (UMRG), National; N Anna Marie (ANNUAL REPORT 2012)
  14. Risk of asthma in children delivered via LSCS, Co-Investigator, 2009-2011, Geran Penyelidikan Universiti Malaya (UMRG), National; De B Jessie
  15. Impact of Asthma action plan on asthmatic exacerbations in children, Co-Investigator, 2008-2009, NONE; De B Jessie
  16. Dust mite sampling in homes of Malaysian children, Principal Investigator(PI), 2008-2008, International Study of Asthma and Allergy in Childhood, International; De B Jessie
  17. Validation of the Asthma Control Test in Children, Co-Investigator, 2008-present, , International; De B Jessie
  18. Specific IgG4 as a Marker of Food Allergy in Children, Co-Investigator, 2008-2008, IPSP, University; De B Jessie
  19. Montelukast in rsv bronchiolitis, Principal Investigator(PI), 2008-2008, Merck & Co., Inc., International; De B Jessie
  20. CFTR in Asian patients with chronic pulmonary disease, Co-Investigator, 2008-2008;National Univesrity S’pore;Institute Paediatric KL; De B Jessie
  21. Helminth Infection and Asthma in the Orang Asli Communities, Co-Investigator, 2007- 2009, ScienceFund 06-01-03; Yvonne Lim, National; De B Jessie
  22. Survey on Bronchiectasis in Paediatric Patients in UMMC., Co-Investigator, 2007-2007, University; De B Jessie
  23. An Observational Follow-up Study of Pediatric Patients Who Participated in a Previous Respiratory Syncitial Virus-Induced Bronchiolitis Study of Montelukast, Principal Investigator(PI), 2007-Present, Merck Sharpe & Dohme (I.A.) Corp, International; De B Jessie
  24. Role of bronchoscopy in ventilator-associated pneumonia, Co-Investigator, 2007-present, , University; De B Jessie
  25. Demographic Pattern of Asthma in Malaysian Children as part of International Study of Asthma and Allergy in Childhood (ISAAC) Phase III, Principal Investigator(PI), 2001-2003, ISAAC coordinating centre New Zealand , International; De B Jessie
  26. Wyeth Lederle Vaccines D153 P511 (Influenza vaccine) Trial, Co-Investigator, 2001-2002, Wyeth Lederle, International; De B Jessie
  27. MOSAIC study A Double-Blind, Randomized, Double-Dummy, Multi-Center Study to Evaluate and Compare Oral Montelukast and Inhaled Fluticasone in the Control of Asthma for 6-14 Year-Olds with Mild Persistent Asthma, Principal Investigator(PI), 2001-2002, Merck & Co Inc, International; De B Jessie
  28. Testing House Dust Mite and Recombinant Dust Mite Allergen Extracts in the Asian Region, Co-Investigator, 2000-2002, CMB & NUS, International; De B Jessie
  29. The use of Tilade in newly-diagnosed asthmatic children with cough, Principal Investigator(PI), 1999-2000, Fisons Malaysia, University; De B Jessie
  30. (i)START Study – Steroid Therapy as Regular Therapy in Early Asthma Principal investigator, Principal Investigator(PI), 1997-2003, Astra International, International; De B Jessie
  31. The effect of inhaled corticosteroid on bone density
  32. Various manifestations of mycoplasma pneumonia
  33. An Observational Follow-up Study of Paediatric Patients Who participated in a Previous Respiratory Syncitial Virus-Induced
    Bronchiolitis Study of Montelukast (Merck Sharpe & Dohme (I.A.) Corp;Jessie de Bruyne).
  34. Evaluation of the Asthma Control Test in Children; Siti Zurina
  35. Impact of a written asthma action plan on asthmatic exacerbations in children; master student project – Wong Su Sien (ANNUAL REPORT 2012)
  36. Drug Utilisation & Drug Policy Study (Use of Antibiotics in Paediatric Tract Infection) (Kanagamalar a/p Subramanian).
  37. Risk of asthma in children delivered via LSCS; Kulenthran s/o Arumugam (O & G); UMRG (ANNUAL REPORT 2012)
  38. Respiratory viruses in children with asthma;master student project – Rakhee Yadav (ANNUAL REPORT 2012)
  39. A 26-Week Randomized, Double-Blinded, Active Controlled Study Comparing the Safety of Mometasone Furoate/FormoterolFumarate MDI Fixed Dose Combination Versus Mometasone Furoate MDI Monotherapy in Adolescents and Adults With Persistent Asthma Merck Sharp & Dohme (ANNUAL REPORT 2012)
  40. A 6-month safety and benefit study of inhaled fluticasone propionate/ salmeterol combination vs inhaled fluticasone propionate in the treatment of 6200 pediatric subjects 4-11years old with persistent asthma Glaxo Smith Kline (ANNUAL REPORT 2012)

Paediatric Trauma/Emergency Unit